MMRV

DiaSorin offers a complete MMRV line, on ELISA format and on LIAISON® systems.

LIAISON® Rubella IgG

The LIAISON® Rubella IgG assay uses chemiluminescence immunoassay (CLIA) technology for the quantitative determination of specific IgG antibodies to rubella virus in human serum or plasma samples. The test has to be performed on the LIAISON® analyzer family.

LIAISON® Mumps IgG

The LIAISON® Mumps IgG assay uses chemiluminescence immunoassay (CLIA) technology for the semi-quantitative determination of specific IgG antibodies to mumps virus in human serum or plasma samples. It is intended to be used as an aid in the determination of serological status to mumps virus. The test has to be performed on the LIAISON® analyzer family.

LIAISON® Measles IgG

The LIAISON® Measles IgG assay uses chemiluminescence immunoassay (CLIA) technology for the semi-quantitative determination of specific IgG antibodies to measles virus in human serum or plasma samples. It is intended to be used as an aid in the determination of serological status to measles virus. The test has to be performed on the LIAISON® analyzer family.

LIAISON® VZV IgG

The LIAISON® VZV IgG assay uses chemiluminescence immunoassay (CLIA) technology for the quantitative determination of specific IgG antibodies to varicella-zoster virus (VZV) in human serum or plasma samples. The test has to be performed on the LIAISON® analyzer family.

Discover LIAISON® MMRV PANEL

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Discover VZV Scientific Booklet

 

MMRV panel is an acronym related to four different viruses:

Measles, a highly contagious virus, transmitted in droplets through coughing and sneezing. Complication include:  encephalitis which occurs in 1 per 1,000 cases of natural measles, will frequently result in permanent brain damage; pneumonia affect approximately 5% of children with measles; 1-3 of every 1,000 children with measles within the United States will die as a result of the disease.
Mumps, a virus spread from person to person by secretions sneezed or coughed from the nose or throat. Complications can include inflamed testicles (20% to 50% of post-pubertal males infected), brain involvement including aseptic meningitis (15% of cases) and inflammation of the pancreas and ovaries.
Rubella, transmitted through mucus droplets in the environment. Rubella in pregnancy can lead to congenital rubella syndrome (CRS) in the fetus. This is characterized by deafness, mental retardation, and heart defects. Up to 85% of expectant mothers infected in the first trimester are at risk of miscarriage or a baby with CRS.
Varicella-zoster, spread through direct contact with fluid from the rash blisters. Chickenpox can cause pneumonia (23 in 10,000 cases) and is a risk factor for developing severe invasive group A streptococcal disease. Complications of varicella include bacterial infections (up to 5% of cases), decreased platelets, arthritis, hepatitis, and brain inflammation (1 in 10,000 cases). If contracted in early pregnancy, VZV can cause abnormalities in 2% of cases.

The MMRV vaccine, a combined vaccine against measles, mumps, rubella and varicella, has been proposed as a replacement for the MMR vaccine to simplify administration of the vaccines.
Regarding immunoassay, MMRV panel consist of Measles, Mumps, Rubella, VZV assays with characteristics to assure superior performance and simple result interpretation. The assays related to the viruses are able to detect IgG antibodies and are calibrated to the WHO International Standards in order to quantitatively measure and follow the course of antibody titres.